CBC, or cannabichromene, is the third most common cannabinoid in cannabis and is the mother of all cannabinoids. It has many potential therapeutic impacts that make it a key player in broad and full-spectrum cannabis products.
CBC is a potent anti-inflammatory that reduces pain by interacting with the body’s receptor system at the spinal level. It also contributes to the general pain-relieving properties of hemp.
Anti-Inflammatory
CBC – cannabichromene CBC – isn’t as well known as THC or CBD, but it offers some promising therapeutic effects. It stems from the same molecule as the others: cannabigerol acid (CBGA).
Cannabichromene CBC doesn’t bind well to the CB1 or CB2 cannabinoid receptors, so it doesn’t elicit a “high.” Instead, it makes its effects felt through other receptors, including those involved in inflammation and pain perception.
CBC has been shown to reduce intestinal motility in a mouse model of inflammation and may help prevent colonic obstruction and stomach cancer. It reduces gastrointestinal contractions without activating cannabinoid receptors or the TRPA1 channel.
Anti-Depressant
The third most prevalent cannabinoid in hemp and cannabis, CBC raises the brain’s natural “bliss” molecule, anandamide, which improves mood and reduces stress. It also has anti-inflammatory properties, and it may help fight cancer.
Like CBD and THC, CBC can be found naturally in marijuana. But, unlike THC, CBC does not have any psychoactive effects.
CBC has been shown to have antidepressant-like effects in behavioral despair models, the FST and TST. Its action was accompanied by decreased immobility time and decreased sluggishness in mice.
Besides affecting mood, CBC has also been shown to have anti-inflammatory effects, specifically through its interaction with TRPV1 receptors on nerve cells. These TRPV1 receptors are triggered by heat, acidity, pressure, and other irritants. As a result, over time, CBC can desensitize these receptors and reduce the release of chemicals that cause inflammation in the body. Moreover, CBC can also promote the production of our endocannabinoids. This is called an entourage effect and is very promising for patients.
Anti-Cancer
CBC is the second most potent cannabinoid inhibiting cancer cell growth (after CBG). It is also a great anti-inflammatory and pain-reducing agent.
Moreover, it may help to regulate the body’s natural regeneration of nerve cells, known as neural stem progenitor cells (NSPCs). It has also been shown to support the body’s ability to balance skin inflammation.
In animal studies, CBC has been found to inhibit the growth of certain kinds of cancers in mice and rats. Moreover, it is thought to help accelerate gastrointestinal cancer cells’ death.
CBC has similar effects as CBD on the body’s natural endocannabinoids, but it interacts with a parallel system of receptors called vanilloid receptor 1 (TRPV1) and transient receptor potential ankyrin 1 (TRPA1). It inhibits the uptake of these endocannabinoids and allows them to remain in the bloodstream longer than usual.
Anti-Aging
What Cannabichromene cbc Can Do
Cannabichromene (CBC) is one of the lesser-known cannabinoids found in cannabis. Unlike THC and CBD, it does not produce psychotropic effects but has several medicinal properties.
Anti-Aging – CBC effectively reduces inflammation and inhibits sebum production by the sebaceous glands. This leads to decreasing blemishes and a brighter complexion.
CBC also has potent anti-microbial properties that are great for fighting various fungi. In addition, CBC can improve stress and moods by naturally interacting with our endocannabinoid system.
Unlike THC, which interacts directly with the CB1 and CB2 cannabinoid receptors in the brain, CBC binds to channels such as the vanilloid receptor 1 (TRPV1) and transient receptor potential ankyrin 1 (TRPA1). These channels are associated with pain and inflammation perception, and natural endocannabinoids like anandamide are released when activated by CBC. These endocannabinoids have a long list of medical benefits, including the ability to stimulate neural stem cells.
